Clone:
37.51
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
hamster IgG2λ, hamster IgG2
Applications:
FA, FC
Alternative names:
T44, Tp44

Specifications for CD28 Antibody, anti-mouse

Overview

The CD28 antibody is specific for the mouse CD28 costimulatory molecule, expressed on most thymocytes, CD4
+
and CD8
+
T cells, and NK cells. Expression is down-regulated at late stages of terminal effector T cell differentiation. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked 45 kDa subunits. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation.

Alternative names

T44, Tp44

Detailed product information

Technical specifications

Clone37.51
Clonalitymonoclonal
Isotypehamster IgG2λ, hamster IgG2
Hosthamster
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenCD28
Alternative names of antigenT44, Tp44
Molecular mass of antigen [kDa]23
Distribution of antigenB cells, T cells, lymphocytes, plasma cells, thymocytes
Entrez Gene ID12487
RRIDAB_1036121, AB_2660825, AB_2660826, AB_1036140

References for CD28 Antibody, anti-mouse

Publications

  1. Gross, J. A. et al. (1992) Identification and distribution of the costimulatory receptor CD28 in the mouse. J. Immunol. 149(2): 380-388
  2. Harding, F. A. et al. (1992) CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356(6370): 607-609

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CD28 Antibody, anti-mouse

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