Choosing the right medium is critical for stem cell culture. With that in mind, we offer an expanding portfolio of proven MACS® and Stemgent® Media for the reliable culture of stem cells and standard eukaryotic cell lines. Our media, cytokines, and growth factors have been optimized to promote healthy morphology and expression of pluripotency markers.
The MACS Media and Stemgent product lines have joined forces to offer a comprehensive selection of ready-to-use cell culture media with a broad range of applications. All of our media are shipped with clear protocols to assist you in efficiently establishing optimal conditions for reprogramming, stem cell expansion, or differentiation.
Application note on NutriStem™ media
We offer a range of cytokines, growth factors, and related proteins where quality and convenience takes precedence. Our cytokines, for example, are available as research-grade, premium-grade, and GMP-grade products – a product range extending from the bench to bedside. Moreover, each batch of premium- and GMP-grade cytokines are ready-to-use and have been tested for biological activity and endotoxin levels.
MACS Cytokines catalog and product list
Small molecules provide an easy and convenient way of manipulating stem cell signaling pathways and have proven to be invaluable effectors of stem and iPS cells. Defined cocktails of small molecules can affect cell reprogramming, self-renewal, and differentiation.
Benefit from a unique portfolio of Stemgent Small Molecules, potent tools that are available in the highest purity (≥98%), have been structurally verified by NMR and mass spectrometry, and have been tested on stem cells for cytotoxicity.
Small molecules with convincing results:
- Tested on stem cells
- Easy cell penetration
- Very low antigenicity
- Easily manipulate signaling pathways and epigenetic modifications
Poster on small molecule signaling pathways
Stemgent’s primary iPS cell and MEF lines are ideal experimental control cells and have been used successfully in many laboratories.
Stem cells require special conditions for survival and growth. An important aspect of this is the underlying matrix. Laminin, a glycosylated protein, can serve as an alternative to mouse embryonic fibroblast (MEF) feeder cells for propagating pluripotent human or mouse cell lines and can be used to support derivation and differentiation of lineage-restricted progenitor cells. Also, pure laminin can support ES and iPS cell growth in the undifferentiated state, when it is desirable to have defined growth conditions. Stemgent Laminin should be used as a cell attachment matrix when growth factors and other contaminants present in less pure RBM gels might compromise an experiment.