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CD71 antibodies, human (clone: AC102)

Overview

The CD71 antibody recognizes the transferrin receptor, which is essential for iron transport into proliferating cells. CD71 is expressed on marrow stromal cells (MSCs) from bone marrow1, on activated T and B lymphocytes, macrophages, and all proliferating cells. It is upregulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, yet it is lost as these differentiate to mature erythrocytes.2,3,4

Technical data


Clone AC102
Isotype mouse IgG2a
Isotype control For the appropriate isotype control antibody, please refer to the tab Related items.
Alternative names of antigen T9, TfR
Entrez Gene ID 7037
Molecular mass of antigen [kDa] 85
Cross-reactivity
Distribution of antigen brain, endothelial cells, mesenchymal stem cells, pluripotent stem cells
Product format Antibodies are supplied in buffer containing stabilizer and 0.05% sodium azide.
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates FITC, PE, APC, Biotin

Gallery

Figure 1

Figure 1
Human cord blood mononuclear cells (CB MNCs) were stained with CD71 antibodies conjugated to PE, as well as with CD45-VioBlue (#130-092-880) and analyzed by flow cytometry. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.
Human cord blood mononuclear cells (CB MNCs) were stained with CD71 antibodies conjugated to PE, as well as with CD45-VioBlue (#130-092-880) and analyzed by flow cytometry. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Figure 2

Human cord blood mononuclear cells (CB-MNCs) were stained with CD71-PE (A) or -APC (B) and CD45-FITC and analyzed by flow cytometry.
A:
B:

Related Items

Library

Selected references

  1. Pittenger, M. F. et al. (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284: 143–147.
  2. Judd, W. et al. (1980) Novel surface antigen expressed on dividing cells but absent from nondividing cells. J. Exp. Med. 152: 1430–1435.
  3. Loken, M. R. et al. (1987) Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood 69: 255–263.
  4. Phillips, J. H. et al. (1984) Natural killer cells activated in a human mixed lymphocyte response culture identified by expression of Leu-11 and class II histocompatibility antigens. J. Exp. Med. 159: 993–1008.

Product Order no. Price

CD71-FITC, human (clone: AC102)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-098-781 $75.00 cart

CD71-FITC, human (clone: AC102)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-098-779 $215.00 cart

CD71-PE, human (clone: AC102)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-219 $90.00 cart

CD71-PE, human (clone: AC102)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-091-728 $255.00 cart

CD71-APC, human (clone: AC102)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-239 $115.00 cart

CD71-APC, human (clone: AC102)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-091-727 $275.00 cart

CD71-Biotin, human (clone: AC102)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-098-900 $75.00 cart

CD71-Biotin, human (clone: AC102)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-098-899 $215.00 cart

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 530 745 2806
macs@miltenyibiotec.com
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