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Exploring the architecture of biology with light sheet microscopy

  • Excellent resolution from overview to cellular level
  • Reduced photodamage
  • Extraordinary imaging speed

Light sheet microscopy allows for fast high-resolution imaging of 3D biological samples, like whole rodent organs, embryos, or larvae. The use of paired orthogonal optical pathways to confine illumination to a single plane allows researchers to image sample volumes faster while limiting light dosage. This technique opens new avenues to study entire biological systems and processes in physiologically representative 3D samples.

Background information