CD97 antibodies, human

CD97 antibodies, human

Clone: REA1242 | Dilution: 1:50
Clone REA1242 reacts with the human CD97 antigen, a member of the epidermal growth factor (EGF)-TM7 family of cell surface receptors. CD97 is expressed by various cell types of the hematopoietic system and also on smooth muscle cells. Highest constitutive expression is found on granulocytes and monocytes. Lymphocytes express CD97 at lower level (T and NK cells expressing higher levels than B cells) but on T cells CD97 is upregulated upon activation via CD3 and CD28 or PHA. CD97 is a ligand for CD55 (decay-accelerating factor, DAF) and has been shown to mediate cell adhesion and co-stimulation of T cell proliferation.
Additional information: Clone REA1242 displays negligible binding to Fc receptors.

Alternative names

ADGRE5, TM7LN1, EMR1

Technical specifications

  • Antigen: CD97
  • Clone: REA1242
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ADGRE5, TM7LN1, EMR1
  • Entrez Gene ID: 976
  • Molecular mass of antigen [kDa]: 90
  • Distribution of antigen: granulocytes, monocytes, B cells, T cells, NK cells, smooth muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, VioBright 515
  • Selected references

    1. Hamann, J. et al. (1995) Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain. J. Immunol. 155(4): 1942-1950
Product options: 8
130-124-979

CD97-PE, human

for 30
tests
(1)
USD 102.00
130-124-969

CD97-PE, human

for 100
tests
(1)
USD 278.00
130-124-980

CD97-APC, human

for 30
tests
(1)
USD 122.00
130-124-970

CD97-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 144.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 135.00
for 100
tests
(1)
USD 385.00