CD9 antibodies, human

CD9 antibodies, human

Clone: REA1071 | Dilution: 1:50
Clone REA1071 recognizes the human CD9 antigen, a 25 kDa cell surface glycoprotein which is also known as tetraspanin-29 (Tspan-29). CD9 belongs to the tetraspanin family of integral proteins, which are characterized by the presence of four conserved transmembrane domains, a small and two large extracellular loops. Expression of CD9 is found on platelets, pre–B cells, fibroblasts, eosinophils, macrophages, basophils, epithelial cells, oocytes, and activated T cells. Further expression is reported on malignant cells and tumor cell lines where CD9 is involved in supressor functions, inhibition of cell invasion and metastasis. CD9 associates with other tetraspanin members, cell adhesion molecules such as EpCAM, integrin subsets, transmembrane proteins (EWI-2 and EWI-F), choline receptors, and G-proteins. Through diverse interactions or via direct stimulation, CD9 influences various cellular functions including cell adhesion, aggregation, migration, clustering of MHC molecules in dendritic cells (DCs), and provides costimulatory signal during T cell activation.
Additional information: Clone REA1071 displays negligible binding to Fc receptors.

Alternative names

5H9, MRP-1, Tetraspanin-29 (Tspan-29), TSPAN-29, p24, MIC3, Tspan29, ORF, GIG2

Technical specifications

  • Antigen: CD9
  • Clone: REA1071
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: 5H9, MRP-1, Tetraspanin-29 (Tspan-29), TSPAN-29, p24, MIC3, Tspan29, ORF, GIG2
  • Entrez Gene ID: 928
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, basophils, eosinophils, epithelial cells, fibroblasts, granulocytes, macrophages, platelets, T cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Hemler, M. E. (2003) Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain. Annu. Rev. Cell Dev. Biol. 19: 397-342
    2. Jones, E. L. et al. (2011) Tetraspanins in cellular immunity. Biochem. Soc. T. 39(2): 506-511
    3. Wang, H. X. et al. (2011) The C-terminal tail of tetraspanin protein CD9 contributes to its function and molecular organization. Cell. Sci. 124: 2702-2710
Product options: 20
130-118-864

CD9-FITC, human

for 30
tests
(1)
USD 82.00
130-118-806

CD9-FITC, human

for 100
tests
(1)
USD 242.00
130-118-865

CD9-PE, human

for 30
tests
(1)
USD 104.00
130-118-807

CD9-PE, human

for 100
tests
(1)
USD 278.00
130-118-866

CD9-APC, human

for 30
tests
(1)
USD 124.00
130-118-808

CD9-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 130.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 162.00
for 100
tests
(1)
USD 345.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 148.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 242.00

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