CD86 antibodies, human

CD86 antibodies, human

Clone: FM95 | Dilution: 1:50
CD86, also known as B7-2 or B70, is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of costimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells (DCs), and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell costimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of costimulatory signals for activation or proliferation of T cells, or cytokine production.

Alternative names

B7-2, B70, CD28LG2, LAB72

Technical specifications

  • Antigen: CD86
  • Clone: FM95
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: B7-2, B70, CD28LG2, LAB72
  • Entrez Gene ID: 942
  • Molecular mass of antigen [kDa]: 35
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, Langerhans cells, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, PerCP-Vio700, Biotin
Product options: 14
130-114-097

CD86-FITC, human

for 30
tests
(1)
USD 82.00
130-113-571

CD86-FITC, human

for 100
tests
(1)
USD 242.00
130-114-098

CD86-PE, human

for 30
tests
(1)
USD 104.00
130-113-572

CD86-PE, human

for 100
tests
(1)
USD 278.00
130-114-095

CD86-APC, human

for 30
tests
(1)
USD 122.00
130-113-569

CD86-APC, human

for 100
tests
(1)
USD 284.00
for 30
tests
(1)
USD 130.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 124.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 242.00

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