CD80 antibodies, mouse

CD80 antibodies, mouse

Clone: 16-10A1 | Dilution: 1:10
The monoclonal antibody 16-10A1 recognizes mouse CD80 also known as B7, B7-1 or Ly-53. The 55 kDa member of the Ig superfamily is expressed on activated B cells, macrophages and dendritic cells. The interaction of CD80 and CD152 (CTLA-4) or CD28 induces T cell proliferation and cytokine production.

Alternative names

B7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1

Technical specifications

  • Antigen: CD80
  • Clone: 16-10A1
  • Isotype: hamster IgG2κ
  • Alternative names of antigen: B7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1
  • Entrez Gene ID: 12519
  • Molecular mass of antigen [kDa]: 30
  • Cross-reactivity: dog
  • Distribution of antigen: B cells, dendritic cells, Langerhans cells, macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin, FITC
  • Selected references

    1. Bluestone, J. A. et al. (1995) New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2(6): 555-559
    2. Hathcock, K. S et al. (1994) Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 180(2): 631-640
    3. Harlan, D. M. et al. (1994) Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proc. Natl. Acad. Sci. U.S.A. 91: 3137-3141
    4. Razi-Wolf, Z. et al. (1992) Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells. Proc. Natl. Acad. Sci. U.S.A. 89: 4210-4214
Product options: 10
130-102-882

CD80-FITC, mouse

9 µg in 300 µL (1)
USD 21.00
130-102-532

CD80-FITC, mouse

30 µg in 1 mL (1)
USD 45.00
130-102-883

CD80-PE, mouse

9 µg in 300 µL (1)
USD 41.00
130-102-613

CD80-PE, mouse

30 µg in 1 mL (1)
USD 55.00
130-102-884

CD80-APC, mouse

9 µg in 300 µL (1)
USD 55.00
130-102-584

CD80-APC, mouse

30 µg in 1 mL (1)
USD 81.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 99.00
9 µg in 300 µL (1)
USD 25.00
30 µg in 1 mL (1)
USD 51.00