CD50 (ICAM-3) antibodies, human

CD50 (ICAM-3) antibodies, human

Clone: REA905 | Dilution: 1:50
Clone REA905 recognizes the human CD50 antigen, a type I transmembrane glycoprotein also known as intercellular adhesion molecule 3 (ICAM-3). As a member of the immunoglobulin superfamily, CD50 is closely related to ICAM-1 and consists of five immunoglobulin domains. It is expressed by leukocytes and is a ligand for CD11a (leukocyte adhesion LFA-1 protein). CD50 is also associated with the amino-terminal domain of ERM proteins and moesin and plays an essential role in primary immune responses.
Additional information: Clone REA905 displays negligible binding to Fc receptors.

Alternative names

Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3

Technical specifications

  • Antigen: CD50 (ICAM-3)
  • Clone: REA905
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3
  • Entrez Gene ID: 3385
  • Molecular mass of antigen [kDa]: 56
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. de Fougerolles, A. R. et al. (1992) Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med. 175(1): 185-190
    2. Serrador, J. M. et al. (2002) A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J. Biol. Chem. 277(12): 10400-10409
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USD 138.00
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tests
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USD 325.00
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 242.00

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