CD48 antibodies, mouse

CD48 antibodies, mouse

Clone: REA1238 | Dilution: 1:50
Clone REA1238 reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150
CD48
CD244
cells, multipotent hematopoietic progenitors are CD244
+
CD150
CD48
and most restricted progenitor cells are CD48
+
CD244
+
CD150
. In mouse, the ligands for CD48 are CD2 and CD244.
Additional information: Clone REA1238 displays negligible binding to Fc receptors.

Alternative names

BCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60

Technical specifications

  • Antigen: CD48
  • Clone: REA1238
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: BCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60
  • Entrez Gene ID: 12506
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: hematopoietic stem cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin, PE
  • Selected references

    1. Latchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J. Immunol. 161: 5809-5812
    2. Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241
    3. Kiel, M.J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121(7): 1109-1121
Product options: 9
130-124-726

CD48-PE, mouse

30 µg in 200 µL (1)
USD 55.00
130-124-727

CD48-APC, mouse

30 µg in 200 µL (1)
USD 80.00
30 µg in 200 µL (1)
USD 115.00
30 µg in 200 µL (1)
USD 135.00
30 µg in 200 µL (1)
USD 135.00
30 µg in 200 µL (1)
USD 140.00
30 µg in 200 µL (1)
USD 135.00
30 µg in 200 µL (1)
USD 180.00
30 µg in 200 µL (1)
USD 55.00