CD47 antibodies, mouse

CD47 antibodies, mouse

Clone: REA170 | Dilution: 1:10
Clone REA170 recognizes CD47, which is also known as integrin-associated protein. CD47 is a 50 KDa heavily glycosylated protein with an extracellular IgV domain, five transmembrane domains and a cytoplasmic tail, which exists in 4 different isoforms. The expression of CD47 varies in different tissue types depending upon the cytoplasmic tail isoform associated, for e.g the 16 amino acid form 2, is expressed in all cells of hematopoietic origin, endothelial and epithelial cells whereas 36 amino acids form 4 is expressed mainly in neurons, intestine, and testis. CD47 can interact with integrins, Thrombospondin-1 (TSP-1), cell surface gylcoproteins SIRPα and SIRPβ. Owing to these interactions, CD47 plays an important role in lymphocyte homeostasis, maturation and activation of dendritic cells, cellular transmigration and phagocytosis of cells.
Additional Information: Clone REA170 displays negligible binding to Fc receptors.

Alternative names

Integrin-associated protein, IAP, Itgp, CD47

Technical specifications

  • Antigen: CD47
  • Clone: REA170
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Integrin-associated protein, IAP, Itgp, CD47
  • Distribution of antigen: B cells, T cells, endothelial cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Demeure, C. E. et al. (2000) CD47 engagement inhibits cytokine production and maturation of human dendritic cells. J. Immunol. 164: 2193-2199
Product options: 16
130-103-109

CD47-FITC, mouse

9 µg in 300 µL (1)
USD 21.00
130-102-538

CD47-FITC, mouse

30 µg in 1 mL (1)
USD 40.00
130-103-108

CD47-PE, mouse

9 µg in 300 µL (1)
USD 40.00
130-102-617

CD47-PE, mouse

30 µg in 1 mL (1)
USD 50.00
130-103-111

CD47-APC, mouse

9 µg in 300 µL (1)
USD 51.00
130-102-591

CD47-APC, mouse

30 µg in 1 mL (1)
USD 76.00
9 µg in 300 µL (1)
USD 59.00
30 µg in 1 mL (1)
USD 116.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 140.00
9 µg in 300 µL (1)
USD 47.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 26.00
30 µg in 1 mL (1)
USD 50.00

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