CD41b antibodies, human

CD41b antibodies, human

Clone: REA336 | Dilution: 1:11
Clone REA336 recognizes the human CD41b antigen, the β chain of integrin α-IIb (CD41). CD41 associates with CD61 to form the heterodimeric GPIIb/GPIIIa complex that is present on human megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin, as well as vitronectin and mediates platelets aggregation.
Additional information: Clone REA336 displays negligible binding to Fc receptors.

Alternative names

ITGA2B, BDPLT16, BDPLT2, GP2B

Technical specifications

  • Antigen: CD41b
  • Clone: REA336
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGA2B, BDPLT16, BDPLT2, GP2B
  • Entrez Gene ID: 3674
  • Molecular mass of antigen [kDa]: 110
  • Distribution of antigen: megakaryocytes, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Gekas, C. et al. (2013) CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 121(22): 4463-4472
    2. Poncz, M. et al. (1987) Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors. J. Biol. Chem. 262(18): 8476-8482
    3. Corbel, C. et al. (2005) (alpha)IIb integrin, a novel marker for hemopoietic progenitor cells. Int. J. Dev. Biol. 49(2-3): 279-284
Product options: 12
for 30
tests
(1)
USD 77.00
for 100
tests
(1)
USD 232.00
130-105-071

CD41b-PE, human

for 30
tests
(1)
USD 97.00
130-105-041

CD41b-PE, human

for 100
tests
(1)
USD 272.00
130-105-072

CD41b-APC, human

for 30
tests
(1)
USD 124.00
130-105-042

CD41b-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 148.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 87.00
for 100
tests
(1)
USD 232.00

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