CD4 antibodies, human

Clone: M-T466 | Dilution: 1:50
CD4 is a type I transmembrane glycoprotein involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. The CD4 molecule is the receptor for the human immunodeficiency virus. The CD4 antibody recognizes the human CD4 antigen which is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. It is responsible for the recognition of the MHC class II antigen.

Alternative names

CD4mut, L3T4, Leu-3, T4

Technical specifications

  • Antigen: CD4
  • Clone: M-T466
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CD4mut, L3T4, Leu-3, T4
  • Entrez Gene ID: 920
  • Molecular mass of antigen [kDa]: 48
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: dendritic cells, granulocytes, Langerhans cells, lymphocytes, macrophages, monocytes, neutrophils, T cells, T helper cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: With the exception of the FITC conjugate the antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Lamprecht, B. et al. (2008) Aberrant expression of the Tʜ2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. Blood 112(8): 3339-3347
    2. Sacha, J. B. et al. (2010)
      Synchronous infection of SIV and HIV
      in vitro
      for virology, immunology and vaccine-related studies.
      Nat. Protoc. 5(2): 239-246
Product options: 18
130-113-815

CD4-FITC, human

for 30
tests
(1)
USD 84.00
130-113-253

CD4-FITC, human

for 100
tests
(1)
USD 248.00
130-113-816

CD4-PE, human

for 30
tests
(1)
USD 108.00
130-113-254

CD4-PE, human

for 100
tests
(1)
USD 284.00
130-113-812

CD4-APC, human

for 30
tests
(1)
USD 128.00
130-113-250

CD4-APC, human

for 100
tests
(1)
USD 294.00
for 30
tests
(1)
USD 134.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 162.00
for 100
tests
(1)
USD 355.00
for 30
tests
(1)
USD 152.00
for 100
tests
(1)
USD 330.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 335.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 335.00
for 30
tests
(1)
USD 84.00
for 100
tests
(1)
USD 248.00

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