CD3ε antibodies – functional grade, mouse

CD3ε antibodies – functional grade, mouse

Clone: 17A2
The monoclonal antibody 17A2 reacts with mouse CD3ε, a part of the CD3 complex and a subunit of the TCR complex, which is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes. Binding of 17A2 antibody to CD3 induces cell activation and proliferation.

Applications

The CD3ε pure – functional grade antibodies are suited for functional assays, for example,
in vitro
T cell activation and expansion, in combination with CD2 and CD28 pure – functional grade antibodies, and
in vivo
T cell depletion.

Alternative names

CD3e, CD3epsilon, T3E, T3

Technical specifications

  • Antigen: CD3ε
  • Clone: 17A2
  • Isotype: rat IgG2bκ
  • Alternative names of antigen: CD3e, CD3epsilon, T3E, T3
  • Entrez Gene ID: 12501
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: NK cells, T cells, thymocytes
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
  • Selected references

    1. Miescher, G. C. et al. (1989) Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. Immunol. Lett. 23(2): 113-118
    2. Exley, M. et al. (1991) Structure, assembly and intracellular transport of the T cell receptor for antigen. Semin. Immunol. 3(5): 283-297
Product options: 1
500 µg in 0.5 mL
USD 360.00