CD34 antibodies, human

CD34 antibodies, human

Clone: REA1164 | Dilution: 1:50
Clone REA1164 recognizes a class III epitope of the CD34 antigen. This epitope is different than the one recognized by the clone used in the CD34 MicroBead Kits.
The CD34 antigen is a single-chain transmembrane glycoprotein, expressed on human hematopoitetic stem and progenitor cells, endothelial progenitor cells, vascular endothelial cells, embryonic fibroblasts, and some cells in fetal and adult nervous tissue. The antigen is absent on fully differentiated hematopoietic cells such as normal peripheral blood lymphocytes, monocytes, granulocytes, erythrocytes, and platelets. CD34 antibodies can be used for studies of hematopoiesis and non-hematopoiectic stem cells, phenotyping of hematopoietic stem cells, and studies on phenotyping of hematologic malignancies, endothelial cells, and endothelial progenitor cells (EPCs).
Additional information: Clone REA1164 displays negligible binding to Fc receptors.

Alternative names

gp105-120, Mucosialin, My10

Technical specifications

  • Antigen: CD34
  • Clone: REA1164
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: gp105-120, Mucosialin, My10
  • Entrez Gene ID: 947
  • Molecular mass of antigen [kDa]: 37
  • Distribution of antigen: endothelial cells, hematopoietic stem cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Stull, R. A. et al. (2000) Simultaneous flow cytometric analyses of enhanced green and yellow fluorescent Cytometry 40: 126-134
    2. Metsuyanim, S. et al. (2009) Expression of stem cell markers in the human fetal kidney. PLoS One 4(68): e6709
    3. De Paepe, M. E. et al. (2011) Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells. Am. J. Pathol. 178(3): 1329-1339
    4. Bility, M. T. et al. (2012) Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis. Nat. Protoc. 7(9): 1608-1617
    5. Vets, S. et al. (2012) Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model. Mol. Ther. 20(5): 908-917
    6. Liu, H. et al. (2013) Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis 4: e857
    7. Lian, W. et al. (2014)
      Varying levels of 6-keto-prostaglandin F1α and thromboxane B2 in serum and endothelialization and hyperplasia in small-diameter grafts seeded with CD34
      +
      bone marrow cells in canines.
      Exp Ther Med. 7(5): 1123-1129
Product options: 19
130-120-520

CD34-PE, human

for 30
tests
(1)
USD 102.00
130-120-515

CD34-PE, human

for 100
tests
(1)
USD 278.00
130-120-519

CD34-APC, human

for 30
tests
(1)
USD 122.00
130-120-514

CD34-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 310.00
for 30
tests
(1)
USD 115.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 300.00
for 30
tests
(1)
USD 144.00
for 100
tests
(1)
USD 315.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 134.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 135.00
for 100
tests
(1)
USD 385.00
for 30
tests
(1)
USD 83.00
for 100
tests
(1)
USD 241.00