CD327 (Siglec-6) antibodies, human

CD327 (Siglec-6) antibodies, human

Clone: REA852 | Dilution: 1:50
Clone REA852 recognizes the human CD327 antigen, which is also known as sialic acid binding Ig-like lectin 6 (Siglec-6), belonging to the Ig superfamily that is involved in cell-cell interactions and signaling. As an adhesion molecule, CD327 mediates sialic acid dependent interaction to cells by binding to the alpha-2,6-linked sialic acid and is highly expressed in placenta and at low levels in spleen, peripheral blood leukocytes, and small intestine.
Additional information: Clone REA852 displays negligible binding to Fc receptors.

Alternative names

CD33 antigen-like 1, CDw327, Obesity-binding protein 1, Siglec-6

Technical specifications

  • Antigen: CD327 (Siglec-6)
  • Clone: REA852
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD33 antigen-like 1, CDw327, Obesity-binding protein 1, Siglec-6
  • Entrez Gene ID: 946
  • Molecular mass of antigen [kDa]: 47
  • Distribution of antigen: placenta, spleen, leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Powell, L. D. et al. (1995) I-type lectins. J. Biol. Chem. 270(24): 14243-14246
    2. Patel, N. et al. (1999) OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily. J. Biol. Chem. 274(32): 22729-22738
    3. Crocker, P. R. et al. (2002) New I-type lectins of the CD 33-related siglec subgroup identified through genomics. Biochem. Soc. Symp. (69): 83-94
Product options: 8
for 30
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for 100
tests
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USD 242.00
for 30
tests
(1)
USD 104.00
for 100
tests
(1)
USD 278.00
for 30
tests
(1)
USD 124.00
for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 240.00

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