CD326 (EpCAM) antibodies, human

CD326 (EpCAM) antibodies, human

Clone: HEA-125 | Dilution: 1:50
Clone HEA-125 recognizes the CD326 antigen, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA), and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts.

Alternative names

EGP40, Ep-CAM, KSA, MK-1, TROP1

Technical specifications

  • Antigen: CD326 (EpCAM)
  • Clone: HEA-125
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: EGP40, Ep-CAM, KSA, MK-1, TROP1
  • Entrez Gene ID: 4072
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: cancer stem cells, epithelial cells, lung, ES and iPS cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, VioBright 667, Biotin
  • Selected references

    1. Moldenhauer, G. et al. (1987) Epithelium specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. Br. J. Cancer 56: 714-721
    2. Metsuyanim, S. et al. (2009) Expression of stem cell markers in the human fetal kidney. PLoS One 4(68): e6709
    3. Sheridan, C. et al. (2006)
      CD44
      +
      /CD24
      -
      breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis.
      Breast Cancer Res. 8(5): R59
  • Brochures and posters

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USD 415.00

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