CD321 (JAM1) antibodies, mouse

CD321 (JAM1) antibodies, mouse

Clone: REA854 | Dilution: 1:50
Clone REA854 recognizes the mouse CD321 antigen, a type I transmembrane glycoprotein containing two extracellular immunoglobulin-like domains. CD321 is a receptor molecule also known as junctional adhesion molecule 1 (JAM1) and is expressed on some epithelial cells, macrophages, and dendritic cells. It is involved in regulating monocyte transmigration as well as in the organization and function of antigen-presenting cells. Furthermore, CD321 acts as a ligand for the integrin LFA1, which plays a role in leukocyte transmigration.
Additional information: Clone REA854 displays negligible binding to Fc receptors.

Alternative names

JAM-A, JAM-1, F11

Technical specifications

  • Antigen: CD321 (JAM1)
  • Clone: REA854
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: JAM-A, JAM-1, F11
  • Entrez Gene ID: 16456
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: epithelial cells, macrophages, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Malergue, F. et al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol. Immunol. 35(17): 1111-1119
    2. Martìn-Padura, I. et al. (1998) Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142(1): 117-127
Product options: 8
30 µg in 200 µL (1)
USD 46.00
150 µg in 1 mL (1)
USD 162.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 190.00
30 µg in 200 µL (1)
USD 80.00
150 µg in 1 mL (1)
USD 320.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 176.00

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