CD300a (LMIR1) antibodies, mouse

CD300a (LMIR1) antibodies, mouse

Clone: REA573 | Dilution: 1:10
Clone REA573 recognizes the mouse CD300a antigen, a type I transmembrane protein of the immunoglobulin superfamily, also known as leukocyte mono-Ig-like receptor1 (LMIR1) or inhibitory receptor protein 60 (IRp60). CD300a plays an important regulatory role in cell signaling and immune responses. It is expressed on monocytes, macrophages, neutrophils, mast cells, NK cells, dendritic cells, and on subsets of T and B lymphocytes.
Additional information: Clone REA573 displays negligible binding to Fc receptors.

Alternative names

CLM-8, Lmir1, MAIR-I, MAIR-Ia, MMAC8, Pigr4, Mcpir1, MAIR-1, IRp60, CMRF-35H

Technical specifications

  • Antigen: CD300a (LMIR1)
  • Clone: REA573
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CLM-8, Lmir1, MAIR-I, MAIR-Ia, MMAC8, Pigr4, Mcpir1, MAIR-1, IRp60, CMRF-35H
  • Entrez Gene ID: 217303
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: monocytes, macrophages, neutrophils, mast cells, NK cells, dendritic cells, T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Cantoni, C. et al. (1999) Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells. Eur. J. Immunol. 29(10): 3148-3159
    2. Yotsumoto, K. et al. (2003) Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J. Exp. Med. 198(2): 223-233
    3. Kumagai, H. et al. (2003) Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells. Biochem. Biophys. Res. Commun. 307(3): 719-729
    4. Bachelet, I. et al. (2005) The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. J. Immunol. 175(12): 7989-7995
Product options: 12
9 µg in 300 µL (1)
USD 79.00
30 µg in 1 mL (1)
USD 164.00
9 µg in 300 µL (1)
USD 36.00
30 µg in 1 mL (1)
USD 51.00
9 µg in 300 µL (1)
USD 51.00
30 µg in 1 mL (1)
USD 75.00
9 µg in 300 µL (1)
USD 47.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 140.00
9 µg in 300 µL (1)
USD 26.00
30 µg in 1 mL (1)
USD 51.00

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