CD298 antibodies, human

CD298 antibodies, human

Clone: REA217 | Dilution: 1:11
Clone REA217 recognizes CD298, the β3 subunit isoform of Na
+
, K
+
-ATPase, which is a membrane associated enzyme. Na
+
, K
+
-ATPase transports Na
+
and K
+
by coupling the hydrolysis of ATP to the transport of Na
+
and K
+
. The movement of ions across the plasma membrane generates and maintains the electrochemical gradient required for osmoregulation, transport of molecules and nutrients. Na
+
, K
+
-ATPase consists of large catalytic α subunit and a smaller glycoprotein non-catalytic β subunit, which exists in three known isoforms.
Additional information: Clone REA217 displays negligible binding to Fc receptors.

Alternative names

ATP1B3, ATPB-3

Technical specifications

  • Antigen: CD298
  • Clone: REA217
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ATP1B3, ATPB-3
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, FITC
  • Selected references

    1. Jørgensen, P. L. et al. (1982)
      Mechanism of the Na
      +
      , K
      +
      pump. Protein structure and conformations of the pure (Na
      +
      , K
      +
      )-ATPase.
      Biochim. Biophys. Acta 694(1): 27-68
    2. Malik, N. et al. (1996) Identification of the mammalian Na,K-ATPase 3 subunit. J. Biol. Chem. 271(37): 22754-22758
    3. Chiampanichayakul, S. et al. (2006) Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells. Tissue Antigens 68(6): 517-509
Product options: 14
130-101-268

CD298-PE, human

for 30
tests
(1)
USD 97.00
130-101-290

CD298-PE, human

for 100
tests
(1)
USD 272.00
130-101-263

CD298-APC, human

for 30
tests
(1)
USD 124.00
130-101-288

CD298-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 300.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 87.00
for 100
tests
(1)
USD 232.00