CD279 (PD1) antibodies, mouse

CD279 (PD1) antibodies, mouse

Clone: REA802 | Dilution: 1:50
Clone REA802 recognizes the mouse CD279 antigen, also known as PD1. CD279 is a member of the Ig superfamily expressed mainly on activated T and B lymphocytes. Expression is induced on activated myeloid cells as well. CD279 is thought to be involved in lymphocyte clonal selection and plays a key role in peripheral tolerance and autoimmune disease in mice. The ligands of CD279, PDL1 (B7-H1) and PDL2 (B7-DC), belong to the B7 immunoglobulin superfamily.
Additional information: Clone REA802 displays negligible binding to Fc receptors.

Alternative names

PDCD1, Ly101, PD1, Pdc1

Technical specifications

  • Antigen: CD279 (PD1)
  • Clone: REA802
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: PDCD1, Ly101, PD1, Pdc1
  • Entrez Gene ID: 18566
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: B cells, monocytes, T cells, spleen, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PerCP-Vio700, Biotin
  • Selected references

    1. Iwai, Y. et al. (2002) Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. U.S.A. 99: 12293-12297
    2. Salama, A. D. et al. (2003) Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J. Exp. Med. 198: 71-78
    3. Hirano, F. et al. (2005) Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunitiy. Cancer Res. 65: 1089-1096
    4. Tsushima, F. et al. (2007) Interaction between B7-H1 and PD-1 determines initiation and reversal of T cell anergy. Blood 110: 180-185
Product options: 10
30 µg in 200 µL (1)
USD 45.00
150 µg in 1 mL (1)
USD 162.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 192.00
30 µg in 200 µL (1)
USD 81.00
150 µg in 1 mL (1)
USD 315.00
30 µg in 200 µL (1)
USD 136.00
150 µg in 1 mL (1)
USD 395.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 178.00

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