CD265 (RANK) antibodies, mouse

CD265 (RANK) antibodies, mouse

Clone: REA961 | Dilution: 1:50
Clone REA961 recognizes the mouse CD265 antigen, also known as receptor activator of NF-κB (RANK) or tumor necrosis factor receptor superfamily member 11A (TNFRSF11A). RANK is the receptor for RANK-ligand (RANKL) which promotes osteoclast differentiation and activation. CD265 is also expressed on dendritic cells, skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, mammary gland epithelial cells, prostate, vascular cells, and pancreas.
Additional information: Clone REA961 displays negligible binding to Fc receptors.

Alternative names

RANK, TRANCE-R, TNFRSF11A

Technical specifications

  • Antigen: CD265 (RANK)
  • Clone: REA961
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: RANK, TRANCE-R, TNFRSF11A
  • Entrez Gene ID: 21934
  • Molecular mass of antigen [kDa]: 63
  • Distribution of antigen: dendritic cells, thymocytes, liver, pancreas, prostate, colon, epithelial cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Anderson, D. M. et al. (1997) A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390(6656): 175-179
    2. Armstrong, A. P. et al. (2002) A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function. J. Biol. Chem. 277(46): 44347-44356
    3. Liu, C. et al. (2010) Structural and functional insights of RANKL-RANK interaction and signaling. J. Immunol. 184(2): 6910-6919
Product options: 7
30 µg in 200 µL (1)
USD 45.00
150 µg in 1 mL (1)
USD 160.00
30 µg in 200 µL (1)
USD 55.00
30 µg in 200 µL (1)
USD 80.00
150 µg in 1 mL (1)
USD 315.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 176.00

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