CD255 (TWEAK) antibodies, mouse

CD255 (TWEAK) antibodies, mouse

Clone: REA1212 | Dilution: 1:50
Clone REA1212 recognizes the mouse CD255 also known as TWEAK which is a type II transmembrane member of the TNF superfamily with a molecular weight of 27 kDa. It is expressed on a variety of cell types and binds to the TWEAK receptor, Fn14. It functions as an inducer of apoptosis in some cell types, promotes angiogenesis and the proliferation of endothelial cells. Furthermore, it is implicated in the induction of inflammatory cytokines.
Additional information: Clone REA1212 displays negligible binding to Fc receptors.

Alternative names

TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Technical specifications

  • Antigen: CD255 (TWEAK)
  • Clone: REA1212
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK
  • Entrez Gene ID: 21944
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: brain, endothelial cells, fibroblasts, heart, lung, lymphocytes, monocytes, ovary, pancreas, skeletal muscle, small intestine, spleen, thymocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE
  • Selected references

    1. Schneider, P. et al. (1999) TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29(6): 1785-1792
    2. Nakayama, M. et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem. Biophys. Res. Commun. 306(4): 819-825
    3. Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459
Product options: 2
30 µg in 200 µL (1)
USD 55.00
30 µg in 200 µL (1)
USD 80.00