CD25 antibodies, mouse

CD25 antibodies, mouse

Clone: 7D4 | Dilution: 1:10
The CD25 antibody recognizes the α chain of the interleukin 2 receptor (IL-2R). IL-2Rα associates with the β chain (CD122) and the γ chain (CD132) to form the functional IL-2R complex. IL-2Rα is expressed on CD4
regulatory T cells, activated T and B cells, and to a lesser extent on activated dendritic cells. It is also transiently expressed during T and B cell development. Binding of the CD25 antibody does not inhibit the binding of IL-2 to its receptor. In combination with CD4, CD25 antibody can be used to identify regulatory T cells (Tregs).

Alternative names

IL2RA, IL2R, Ly-43, IL-2Rα, p55, Tac

Technical specifications

  • Antigen: CD25
  • Clone: 7D4
  • Isotype: rat IgMκ
  • Isotype control: Rat IgM – isotype control antibodies
  • Alternative names of antigen: IL2RA, IL2R, Ly-43, IL-2Rα, p55, Tac
  • Entrez Gene ID: 16184
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: B cells, basophils, lymphocytes, macrophages, monocytes, myeloid cells, NK cells, osteoblasts, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin, VioBright FITC
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