CD25 antibodies, human

CD25 antibodies, human

Clone: REA570 | Dilution: 1:50
Clone REA570 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). It associates with IL-2 receptor β (CD122) and γ chains (CD132) to form a high affinity IL-2R complex. CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4
+
regulatory T cells. Clone REA570 recognizes epitope region A.
Additional information: Clone REA570 displays negligible binding to Fc receptors

Alternative names

IL2RA, IDDM10, IL2R, TCGFR, p55, Tac

Technical specifications

  • Antigen: CD25
  • Clone: REA570
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: IL2RA, IDDM10, IL2R, TCGFR, p55, Tac
  • Entrez Gene ID: 3559
  • Molecular mass of antigen [kDa]: 55
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: T cells, B cells, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, VioBright 515, Biotin, PE-Vio615
  • Selected references

    1. Lee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J. Immunol. 189(6): 2712-2716
    2. Piccirillo, C. A. et al. (2006)
      Development and function of naturally occurring CD4
      +
      CD25
      +
      regulatory T cells.
      J. Leukoc. Biol. 3: 458-470
    3. Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146(3): 248-261
Product options: 12
130-113-848

CD25-PE, human

for 30
tests
(1)
USD 104.00
130-113-286

CD25-PE, human

for 100
tests
(1)
USD 278.00
130-113-846

CD25-APC, human

for 30
tests
(1)
USD 122.00
130-113-284

CD25-APC, human

for 100
tests
(1)
USD 284.00
for 30
tests
(1)
USD 144.00
for 100
tests
(1)
USD 310.00
for 30
tests
(1)
USD 135.00
for 100
tests
(1)
USD 385.00
for 30
tests
(1)
USD 81.00
for 100
tests
(1)
USD 238.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 300.00

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