CD229 (Ly-9) antibodies, human

CD229 (Ly-9) antibodies, human

Clone: Hly9.1.25 | Dilution: 1:11
Clone Hly9.1.25 reacts with CD229, a type I transmembrane glycoprotein belonging to the CD150 subfamily of leukocyte receptors of the Ig superfamily. CD229 has four extracellular Ig domains and a cytoplasmic domain containing two copies of the tyrosine-based motif (T-I/V-Y-x-x-V/I). Via this unique motif, CD229 interacts with SH2-binding phosphatases and the adapter molecules SAP, EAT-2, and Grb2. Expression of CD229 is found on T cells, B cells, NK cells, and thymocytes. CD229 interacts homophilically via its N-terminal V-like domain and is involved in enhancing T cell activation and Tʜ2 polarization.

Alternative names

Ly-9, SLAMF3, hly9, mLY9

Technical specifications

  • Antigen: CD229 (Ly-9)
  • Clone: Hly9.1.25
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Ly-9, SLAMF3, hly9, mLY9
  • Entrez Gene ID: 4063
  • Molecular mass of antigen [kDa]: 67
  • Distribution of antigen: B cells, T cells, NK cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin, PE, APC, PE-Vio770
  • Selected references

    1. Martín, M. et al. (2005) Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. J. Immunol. 174: 5977-5986
    2. Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J. Immunol. 174(11): 7033-7042
    3. Romero, X. et al. (2004) Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 64(2): 132-144
Product options: 8
for 30
tests
USD 97.00
for 100
tests
USD 272.00
for 30
tests
USD 124.00
for 100
tests
USD 288.00
for 30
tests
USD 142.00
for 100
tests
USD 305.00
for 30
tests
USD 87.00
for 100
tests
USD 232.00

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