CD20 antibodies, human

CD20 antibodies, human

Clone: LT20 | Dilution: 1:50
The antibody recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca
2+
channel and might function in the regulation of local responses during B cell activation.

Alternative names

MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44

Technical specifications

  • Antigen: CD20
  • Clone: LT20
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44
  • Entrez Gene ID: 931
  • Molecular mass of antigen [kDa]: 33
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, cancer stem cells, dendritic cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PerCP, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, PE-Vio615
  • Selected references

    1. Lamprecht, B. et al. (2008) Aberrant expression of the Tʜ2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. Blood 112(8): 3339-3347
    2. Maxwell, S. A. et al. (2009) 14-3-3zeta J. Biol. Chem. 284(33): 22379-22389
    3. Countouriotis, T. B. et al. (2002) Cell surface antigen and molecular targeting in the treatment of hematologic malignancies. Stem Cells 20(3): 215-229
    4. Cragg, M. S. et al. (2002)
      Opposing properties of CD20 mAb; in: Mason, D.
      et al.
      (eds.): Leucocyte typing VII,
      Oxford, Oxford University Press
    5. Polyak, M. J. and Deans, J. P. (2002)
      CD20 Workshop Panel report: in Mason, D.
      et al.
      (eds.): Leucocyte typing VII,
      Oxford, Oxford University Press
Product options: 22
130-113-935

CD20-FITC, human

for 30
tests
(1)
USD 82.00
130-113-373

CD20-FITC, human

for 100
tests
(1)
USD 242.00
130-113-936

CD20-PE, human

for 30
tests
(1)
USD 102.00
130-113-374

CD20-PE, human

for 100
tests
(1)
USD 274.00
130-113-932

CD20-APC, human

for 30
tests
(1)
USD 122.00
130-113-370

CD20-APC, human

for 100
tests
(1)
USD 284.00
for 30
tests
(1)
USD 130.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 162.00
for 100
tests
(1)
USD 345.00
for 30
tests
(1)
USD 120.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 148.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 134.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 81.00
for 100
tests
(1)
USD 238.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00

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