CD183 (CXCR3) antibodies, rat

CD183 (CXCR3) antibodies, rat

Clone: REA874 | Dilution: 1:50
Clone REA874 recognizes the rat CD183 antigen, also known as CXCR3. CD183 is a member of the CXC chemokine receptor family and is found on activated T cells, B cells, and NK cells during inflammation. CD183 plays a critical role in T cell migration and is important for activated T lymphoblast recruitment. It mediates the proliferation, survival, and angiogenic activity, and functions as a 7-transmembrane spanning receptor for the CXC chemokines CXCL9, CXCL10, and CXCL11.
Additional information: Clone REA874 displays negligible binding to Fc receptors.

Alternative names

CXCR3, CXC-R3, CXCR-3, IP-10 receptor

Technical specifications

  • Antigen: CD183 (CXCR3)
  • Clone: REA874
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CXCR3, CXC-R3, CXCR-3, IP-10 receptor
  • Entrez Gene ID: 84475
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: T cells, B cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Wang, X. et al. (2000) Identification and molecular characterization of rat CXCR3: receptor expression and interferon-inducible protein-10 binding are increased in focal stroke. Mol. Pharmacol. 57(6): 1190-1198
    2. Mohan, K. et al. (2005)
      CXCR3 is required for migration to dermal inflammation by normal and
      in vivo
      activated T cells: differential requirements by CD4 and CD8 memory subsets.
      Eur. J. Immunol. 35(6): 1702-1711
    3. Sporici, R. et al. (2010) CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease. Eur. J. Immunol. 40(10): 2751-2761
Product options: 8
30 µg in 200 µL (1)
USD 46.00
150 µg in 1 mL (1)
USD 162.00
30 µg in 200 µL (1)
USD 55.00
150 µg in 1 mL (1)
USD 192.00
30 µg in 200 µL (1)
USD 81.00
150 µg in 1 mL (1)
USD 315.00
30 µg in 200 µL (1)
USD 56.00
150 µg in 1 mL (1)
USD 178.00

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