CD16 antibodies, human

CD16 antibodies, human

Clone: REA423 | Dilution: 1:50
Clone REA423 recognizes the human CD16 antigen, a single-pass type I membrane protein which is also known as low affinity immunoglobulin gamma Fc region receptor III (FcRIII). CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils. The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone REA423 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes.
Additional information: Clone REA423 displays negligible binding to Fc receptors.

Alternative names

FCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII

Technical specifications

  • Antigen: CD16
  • Clone: REA423
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII
  • Entrez Gene ID: 2214, 2215
  • Molecular mass of antigen [kDa]: 48
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    , capuchin monkey,
    chimpanzee (
    Pan troglodytes
    )
    ,
    common marmoset (
    Callithrix jacchus
    )
    ,
    cotton-top tamarin (
    Saguinus oedipus
    )
    ,
    olive baboon (
    Papio anubis
    )
    ,
    pigtail monkey (
    Macaca nemestrina
    )
    ,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: NK cells, monocytes, granulocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, VioBright 515, PE-Vio615
Product options: 22
130-113-954

CD16-FITC, human

for 30
tests
(1)
USD 84.00
130-113-392

CD16-FITC, human

for 100
tests
(1)
USD 248.00
130-113-955

CD16-PE, human

for 30
tests
(1)
USD 144.00
130-113-393

CD16-PE, human

for 100
tests
(1)
USD 280.00
130-113-951

CD16-APC, human

for 30
tests
(1)
USD 108.00
130-113-389

CD16-APC, human

for 100
tests
(1)
USD 290.00
for 30
tests
(1)
USD 128.00
for 100
tests
(1)
USD 302.00
for 30
tests
(1)
USD 166.00
for 100
tests
(1)
USD 355.00
for 30
tests
(1)
USD 148.00
for 100
tests
(1)
USD 320.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 335.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 84.00
for 100
tests
(1)
USD 248.00
for 30
tests
(1)
USD 170.00
for 100
tests
(1)
USD 425.00
for 30
tests
(1)
USD 146.00
for 100
tests
(1)
USD 315.00

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