CD158e/k (KIR3DL1/DL2) antibodies, human

CD158e/k (KIR3DL1/DL2) antibodies, human

Clone: REA970 | Dilution: 1:50
Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell–mediated cytotoxicity. Expression is found mainly on CD56
dim
CD16
+
natural killer (NK) cells but also on a subset of CD8
+
T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.
Additional information: Clone REA970 displays negligible binding to Fc receptors.

Alternative names

KIR3DL1, KIR3DL2

Technical specifications

  • Antigen: CD158e/k (KIR3DL1/DL2)
  • Clone: REA970
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR3DL1, KIR3DL2
  • Entrez Gene ID: 3811
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Yawata, M. et al. (2002) Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit. Rev. Immunol. 22(5–6): 463-482
    2. Uhrberg, M. (2005) The KIR gene family: life in the fast lane of evolution. Eur. J. Immunol. 35(1): 10-15
  • Customer reports and application notes

Product options: 13
for 30
tests
(1)
USD 81.00
for 100
tests
(1)
USD 238.00
for 30
tests
(1)
USD 102.00
for 100
tests
(1)
USD 274.00
for 30
tests
(1)
USD 122.00
for 100
tests
(1)
USD 284.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 296.00
for 30
tests
(1)
USD 144.00
for 100
tests
(1)
USD 310.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 81.00
for 100
tests
(1)
USD 238.00

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