CD158a (KIR2DL1) antibodies, human

CD158a (KIR2DL1) antibodies, human

Clone: REA284 | Dilution: 1:50
Clone REA284 recognizes human CD158a (KIR2DL1), but not KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1. CD158a is 58 kDa protein, also known as KIR2DL1. CD158a is a member of the family of killer cell immunoglobulin-like receptors (KIRs) comprising transmembrane glycoproteins expressed on NK cells and a subset of T cells. Many groups of KIRs exist including KIR3DL1-3, KIR3DS1, KIR2DL1-5, and KIR2DS1-5. The isoforms have either a short (S) or long (L) cytoplasmic domain which transduce either an activating or inhibitory signal, respectively. The ligands of CD158a (KIR2DL1) are HLA-C molecules with Asn77 and Lys80, but not Ser77 and Asn80.
Additional information: Clone REA284 displays negligible binding to Fc receptors.

Alternative names

KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1

Technical specifications

  • Antigen: CD158a (KIR2DL1)
  • Clone: REA284
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1
  • Entrez Gene ID: 3802
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC-Vio770, PE, APC, PE-Vio770, Biotin
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