CD148 antibodies, human

CD148 antibodies, human

Clone: REA204 | Dilution: 1:11
Clone REA204 recognizes CD148, a receptor type protein tyrosine phosphatase (PTP) belonging to the type III family of PTPs. CD148 is characterized by an extracellular domain with eight fibronectin type III repeats, a trans-membrane region, and a single cytosolic catalytic domain. Expression of CD148 is found on mature thymocytes, peripheral T cells, B cells, NK cells, granulocytes, macrophages, DC subpopulations, epithelial and endothelial cells, and fibroblasts. An upregulated expression of CD148 on human peripheral T cells is observed upon TCR stimulation. CD148 via regulating the phosphorylation status of substrates such as PDGFR, p120 catenin (CTND1), and SRC kinase, plays vital role in many cellular functions.
Additional information: Clone REA204 displays negligible binding to Fc receptors.

Alternative names

PTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1

Technical specifications

  • Antigen: CD148
  • Clone: REA204
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PTPRJ, DEP1, HPTPeta, R-PTP-ETA, SCC1
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, Biotin, FITC
  • Selected references

    1. Tangye, S. G. et al. (1998) CD148: A receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation. J. Immunol. 161: 3249-3255
    2. de la Fuente-García, M. A. et al. (1998) CD148 is a membrane protein tyrosine phosphatase present in all hematopoietic lineages and is involved in signal transduction on lymphocytes. Blood 91: 2800-2809
Product options: 12
for 30
tests
(1)
USD 77.00
for 100
tests
(1)
USD 232.00
130-101-246

CD148-PE, human

for 30
tests
(1)
USD 97.00
130-101-222

CD148-PE, human

for 100
tests
(1)
USD 272.00
130-101-183

CD148-APC, human

for 30
tests
(1)
USD 124.00
130-101-181

CD148-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 87.00
for 100
tests
(1)
USD 232.00

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