CD142 antibodies, human

CD142 antibodies, human

Clone: HTF-1 | Dilution: 1:11
The monoclonal antibody HTF-1 recognizes the 45 kDa type I transmembrane glycoprotein also known as TF (tissue factor). It functions as the high-affinity receptor for the coagulation factor VII and enables cells to initiate the blood coagulation cascades. It is reported, that the tissue factor exists in a membrane-bound and in a soluble form. It is expressed on activated endothelial cells and on monocytes, macrophages, and platelets, which are stimulated with inflammatory mediators such as LPS or TNF alpha. CD142 is also present on some tumor cells such as lung, breast, pancreatic, and colon, and on non-immune-tissues.

Alternative names

F3, Tissue Factor (TF), TF, TFA, CD142

Technical specifications

  • Antigen: CD142
  • Clone: HTF-1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: F3, Tissue Factor (TF), TF, TFA, CD142
  • Entrez Gene ID: 2152
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: endothelial cells, epithelial cells, fibroblasts, liver, monocytes, pancreas, ES and iPS cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Carson, S. D. et al. (1994) Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity. Blood 84: 526-534
    2. Bogdanov, V. Y. et al. (2003) Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat. Med. 9: 458-462
    3. Butenas, S. et al. (2008) Tissue factor activity and function in blood coagulation. Thromb. Res. 122: S42-S46
    4. Golino, P. et al. (2002) The inhibitors of the tissue factor: factor VII pathway. Thromb. Res. 106(3): V257-V265
Product options: 18
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 232.00
130-098-743

CD142-PE, human

for 30
tests
(1)
USD 97.00
130-098-742

CD142-PE, human

for 100
tests
(1)
USD 272.00
130-098-745

CD142-APC, human

for 30
tests
(1)
USD 124.00
130-098-744

CD142-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 300.00
for 30
tests
(1)
USD 152.00
for 100
tests
(1)
USD 335.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 132.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 87.00
for 100
tests
(1)
USD 232.00

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