CD140a antibodies, human

CD140a antibodies, human

Clone: REA911 | Dilution: 1:50
Clone REA911 recognizes the human CD140a single transmembrane glycoprotein, also known as platelet derived growth factor (PDGF) receptor α. CD140 a is a tyrosine-protein kinase which functions as a cell-surface receptor for PDGFA, PDGFB, and PDGFC and is involved in the regulation of embryonic development, cell proliferation, survival, and chemotaxis. CD140a is found on platelets, fibroblasts, smooth muscle cells, glial cells, and chondrocytes as well as in brain, heart, embryo, colon tumors, and in normal colon tissues.
Additional information: Clone REA911 displays negligible binding to Fc receptors.

Alternative names

Pdgfr-2, PDGFR-alpha

Technical specifications

  • Antigen: CD140a
  • Clone: REA911
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Pdgfr-2, PDGFR-alpha
  • Entrez Gene ID: 5156
  • Molecular mass of antigen [kDa]: 120
  • Distribution of antigen: smooth muscle, brain, heart, colon
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Matsui, T. et al. (1989) Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways. Proc. Natl. Acad. Sci. U.S.A. 86(21): 8314-8318
    2. Kawagishi, J. et al. (1995) Structure, organization, and transcription units of the human alpha-platelet-derived growth factor receptor gene, PDGFRA. Genomics 30(2): 224-232
    3. Craven, R. J. et al. (1995) Receptor tyrosine kinases expressed in metastatic colon cancer. Int. J. Cancer 60(6): 791-797
Product options: 14
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 242.00
130-115-337

CD140a-PE, human

for 30
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(1)
USD 104.00
130-115-238

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for 100
tests
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for 30
tests
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USD 82.00
for 100
tests
(1)
USD 242.00

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