CD137 antibodies, human

CD137 antibodies, human

Clone: REA765 | Dilution: 1:50
Clone REA765 recognizes the human CD137 antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily, a group of cytokines that can cause cell death (apoptosis). CD137 is mainly expressed on activated CD4
+
and CD8
+
T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. As a costimulatory molecule it is involved in the activation and survival of CD4
+
or CD8
+
T cells and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8
+
T cells, as it is not expressed on resting CD8
+
T cells and its expression is reliably induced after 24 hours of stimulation.
Additional information: Clone REA765 displays negligible binding to Fc receptors.

Alternative names

CDw137, TNFRSF9, ILA, Ly-63, 4-1BB

Technical specifications

  • Antigen: CD137
  • Clone: REA765
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CDw137, TNFRSF9, ILA, Ly-63, 4-1BB
  • Entrez Gene ID: 3604
  • Molecular mass of antigen [kDa]: 25
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, lymphocytes, macrophages, monocytes, fibroblasts, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio615, VioBright 515, Biotin
Product options: 12
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 345.00
130-110-900

CD137-PE, human

for 30
tests
(1)
USD 97.00
130-110-763

CD137-PE, human

for 100
tests
(1)
USD 272.00
130-110-901

CD137-APC, human

for 30
tests
(1)
USD 124.00
130-110-764

CD137-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 166.00
for 100
tests
(1)
USD 415.00
for 30
tests
(1)
USD 77.00
for 100
tests
(1)
USD 232.00

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