CD134 (OX40) antibodies, mouse

CD134 (OX40) antibodies, mouse

Clone: REA625 | Dilution: 1:10
Clone REA625 recognizes the CD134 antigen, also known as OX40 receptor, a 50 kDa type I membrane glycoprotein of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. OX40 is a secondary costimulatory molecule, which is expressed after 24 to 72 hours following activation. It is expressed on activated mouse T cells and B cells. The OX40 receptor binds to the OX40 ligand (CD252) to provide a costimulatory signal which is independent of CD28.
Additional information: Clone REA625 displays negligible binding to Fc receptors.

Alternative names

OX40L receptor, OX-40, TNFRSF4

Technical specifications

  • Antigen: CD134 (OX40)
  • Clone: REA625
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: OX40L receptor, OX-40, TNFRSF4
  • Entrez Gene ID: 22163
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699
    2. Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
    3. Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
    4. Hong, G. U. et al. (2015) IgE and IgA produced by OX40-OX40L or CD40-CD40L interaction in B cells-mast cells re-activate FcεRI or FcαRI on mast cells in mouse allergic asthma. Eur. J. Pharmacol. 754: 199-210
  • Customer reports and application notes

Product options: 7
9 µg in 300 µL (1)
USD 36.00
30 µg in 1 mL (1)
USD 51.00
9 µg in 300 µL (1)
USD 50.00
30 µg in 1 mL (1)
USD 76.00
9 µg in 300 µL (1)
USD 47.00
30 µg in 1 mL (1)
USD 136.00
30 µg in 1 mL (1)
USD 50.00

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