CD127 antibodies, human

CD127 antibodies, human

Clone: MB15-18C9 | Dilution: 1:50
Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the interleukin 7 (IL-7) receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc). CD127 can be identified on immature B cells through the early pre–B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation. On regulatory T cells CD127 is absent and its expression is inversely correlated with FoxP3 expression and suppressive function. CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex.

Alternative names

IL-7R, IL-7Rα, CDW127, ILRA

Technical specifications

  • Antigen: CD127
  • Clone: MB15-18C9
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: IL-7R, IL-7Rα, CDW127, ILRA
  • Entrez Gene ID: 3575
  • Molecular mass of antigen [kDa]: 49
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, bone marrow, liver, lymphocytes, monocytes, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, Biotin
  • Selected references

    1. Sudo, T. et al. (1993) Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 90: 9125-9129
Product options: 12
for 30
tests
(1)
USD 83.00
for 100
tests
(1)
USD 244.00
130-113-972

CD127-PE, human

for 30
tests
(1)
USD 108.00
130-113-410

CD127-PE, human

for 100
tests
(1)
USD 284.00
130-113-969

CD127-APC, human

for 30
tests
(1)
USD 128.00
130-113-407

CD127-APC, human

for 100
tests
(1)
USD 294.00
for 30
tests
(1)
USD 146.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 152.00
for 100
tests
(1)
USD 330.00
for 30
tests
(1)
USD 84.00
for 100
tests
(1)
USD 248.00

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