CD116 antibodies, human

CD116 antibodies, human

Clone: REA211 | Dilution: 1:11
Clone REA211 recognizes CD116, the α subunit of GM-CSF receptor, which serves as a receptor for GM-CSF cytokine. GM-CSF is involved in innate and adaptive immune responses to infection, stimuli such as presence of LPS, and inflammatory diseases, such as asthma, rheumatoid arthritis, and multiple sclerosis. The GM-CSF receptor comprises of cytokine-specific α subunit, CD116, and βc subunit, which is a common subunit shared by interleukin-3 (IL-3) and IL-5. The human CD116 is a 378 residue glycoprotein with an extracellular N-terminal Ig-like domain, two fibronectin (FnIII) domains, and a 54 residue intracellular domain. Expression of CD116 is found on myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells, fibroblasts, endothelial cells, and myeloid leukemias.
Additional information: Clone REA211 displays negligible binding to Fc receptors.

Alternative names

CSF2RA, GM-CSF-R-α

Technical specifications

  • Antigen: CD116
  • Clone: REA211
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CSF2RA, GM-CSF-R-α
  • Distribution of antigen: macrophages, monocytes, dendritic cells, fibroblasts, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

Product options: 14
for 30
tests
(1)
USD 79.00
for 100
tests
(1)
USD 238.00
130-101-011

CD116-PE, human

for 30
tests
(1)
USD 99.00
130-101-008

CD116-PE, human

for 100
tests
(1)
USD 278.00
130-100-986

CD116-APC, human

for 30
tests
(1)
USD 128.00
130-100-984

CD116-APC, human

for 100
tests
(1)
USD 294.00
for 30
tests
(1)
USD 146.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 136.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 136.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 89.00
for 100
tests
(1)
USD 238.00

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