CD111 antibodies, human

CD111 antibodies, human

Clone: R1.302 | Dilution: 1:11
Clone R1.302 recognizes the CD111 antigen, a 75 kDa type I transmembrane glycoprotein also known as poliovirus receptor related 1 protein (PRR1), PVRL1, HveC, and Nectin-1. Nectins are involved in the formation of the mechanical adhesive puncta adherentia junctions of synapses. CD111 is an adhesion molecule that can be found in a wide range of tissues where it localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons. In the chemical synapse, CD111 interacts with PVRL3 and both proteins can be found in neuronal tissue already in early stages of brain development as well as in aging brains. CD111 also functions as an entry receptor for herpes simplex virus and pseudorabies virus.

Alternative names

PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1

Technical specifications

  • Antigen: CD111
  • Clone: R1.302
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1
  • Entrez Gene ID: 5818
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Cocchi, F. et al. (1998) The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D. Proc. Natl. Acad. Sci. U.S.A. 95(26): 15700-15705
    2. Rikitake, Y. et al. (2012) The role of nectins in different types of cell-cell adhesion. J. Cell. Sci. 125: 3713-3722
    3. Takahashi, K. et al. (1999) Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J. Cell Biol. 145(3): 539-549
Product options: 10
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 355.00
130-103-903

CD111-PE, human

for 30
tests
(1)
USD 97.00
130-103-833

CD111-PE, human

for 100
tests
(1)
USD 272.00
130-103-904

CD111-APC, human

for 30
tests
(1)
USD 124.00
130-103-834

CD111-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 30
tests
(1)
USD 87.00
for 100
tests
(1)
USD 232.00

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