CD101 antibodies, human

CD101 antibodies, human

Clone: BB27 | Dilution: 1:11
Clone BB27 recognizes the CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5–30% of FoxP3
+
Treg cells in peripheral blood.
The interaction of CD101 with the antibody BB27 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies.

Alternative names

EWI-101, IGSF2, V7, p126

Technical specifications

  • Antigen: CD101
  • Clone: BB27
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: EWI-101, IGSF2, V7, p126
  • Entrez Gene ID: 9398
  • Molecular mass of antigen [kDa]: 113
  • Distribution of antigen: dendritic cells, granulocytes, Langerhans cells, leukemia cells, lung, lymphocytes, monocytes, red blood cells, small intestine, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Rivas, A. et al. (1995) V7, a novel leukocyte surface protein that participates in T cell activation. J. Immunol. 154: 4423-4433
    2. Soares, L. R. et al. (1998)
      V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca
      2+
      flux and nuclear factor of activated T cell nucleartranslocation.
      J. Immunol. 161: 209-217
    3. Bouloc, A. et al. (2000) Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production. Eur. J. Immunol. 30: 3132-3139
    4. Bagot, M. et al. (1997) CD101 is expressed by skin dendritic cells: role in T-lymphocyte activation. Tissue Antigens 50: 439-448
Product options: 7
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 345.00
130-095-225

CD101-PE, human

for 100
tests
(1)
USD 272.00
130-095-132

CD101-APC, human

for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 142.00
for 100
tests
(1)
USD 305.00
for 100
tests
(1)
USD 232.00

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