Anti-TOM22 antibodies, human and mouse

Anti-TOM22 antibodies, human and mouse

Clone: REA1185 | Dilution: 1:50
Clone REA1185 recognizes the human and mouse mitochondrial import receptor subunit TOM22 homolog antigen, a single-pass membrane protein which is also known as translocase of outer membrane 22 kDa subunit homolog. TOM22 is a central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. It functions together with the peripheral receptor TOM20 as the transit peptide receptor and facilitates the movement of pre-proteins into the translocation pore.
Additional information: Clone REA1185 displays negligible binding to Fc receptors.

Alternative names

hTom22, 1C9-2, Tomm22

Technical specifications

  • Antigen: TOM22
  • Clone: REA1185
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: hTom22, 1C9-2, Tomm22
  • Entrez Gene ID: 56993, 223696, 300075
  • Molecular mass of antigen [kDa]: 15
  • Cross-reactivity: rat
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. Shiota, T. et al. (2011)
      In vivo
      protein-interaction mapping of a mitochondrial translocator protein Tom22 at work.
      Proc. Natl. Acad. Sci. U.S.A. 108(37): 15179-15183
    2. Bellot, G. et al. (2007) TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ. 14(4): 785-794
    3. Yano. M. et al. (2000) Identification and functional analysis of human Tom22 for protein import into mitochondria. Mol. Cell. Biol. 20(19): 7205-7213
Product options: 4
for 30
tests
(1)
USD 102.00
for 100
tests
(1)
USD 278.00
for 30
tests
(1)
USD 122.00
for 100
tests
(1)
USD 288.00

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