Anti-TCRα/β antibodies, human

Anti-TCRα/β antibodies, human

Clone: REA652 | Dilution: 1:50
Clone REA652 recognizes the human α/β T cell receptor (TCR). The T cell receptor is a heterodimer composed of two transmembrane glycoprotein chains, α and β. In 95% of T cells the TCR consists of an α and β chain, whereas in 5% of T cells it has γ and δ chains. α and β chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells.
Additional information: Clone REA652 displays negligible binding to Fc receptors.

Alternative names

TCR a/b, IMD7, TCRA, TRAC, TRA, TRB

Technical specifications

  • Antigen: TCRα/β
  • Clone: REA652
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR a/b, IMD7, TCRA, TRAC, TRA, TRB
  • Entrez Gene ID: 6955, 6957
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, APC-Vio770, PerCP-Vio700, Biotin, VioBlue, VioGreen, PE-Vio770
  • Selected references

    1. Brenner, M. B. et al. (1986) Identification of a putative second T-cell receptor. Nature 322(6075): 145-149
    2. Call, M. E. et al. (2002) The organizing principle in the formation of the T cell receptor-CD3 complex. Cell 111(7): 967-979
    3. Oettgen, H. C. et al. (1984) Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. J. Biol. Chem. 259(19): 12039-12048
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