Anti-TCR Vβ8.1, 8.2 antibodies, mouse

Anti-TCR Vβ8.1, 8.2 antibodies, mouse

Clone: REA585 | Dilution: 1:10
Clone REA585 recognizes the mouse Vβ8.1, 8.2 T cell receptor (TCR Vβ8.1, 8.2) but not Vβ8.3. Vβ8.1 and 8.2 are variants of the TCR β chain that associates with the TCR α chain. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains. TCR Vβ8.1, 8.2 is expressed on approximately 20 % of peripheral T cells in thymus, spleen, and other lymphoid organs in different mice strains, such as Balb/c, AKR, C57BL/6, AKR/B10.A.
Additional information: Clone REA585 displays negligible binding to Fc receptors

Alternative names

TCR Vb8.1, 8.2, TCR Vbeta8.1, 8.2

Technical specifications

  • Antigen: TCR Vβ8.1, 8.2
  • Clone: REA585
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb8.1, 8.2, TCR Vbeta8.1, 8.2
  • Entrez Gene ID: 100124677, 100124675
  • Molecular mass of antigen [kDa]: 13
  • Distribution of antigen: T cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Haskins, K. et al. (1984) The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160(2): 452-471
    2. Kuchroo, V. K. et al. (1994) T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. J. Exp. Med. 179(5): 1659-1664
    3. Mami-Chouaib, F. et al. (2002) Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen. Immunol. Rev. 188: 114-121
Product options: 12
9 µg in 300 µL (1)
USD 20.00
30 µg in 1 mL (1)
USD 40.00
9 µg in 300 µL (1)
USD 35.00
30 µg in 1 mL (1)
USD 50.00
9 µg in 300 µL (1)
USD 50.00
30 µg in 1 mL (1)
USD 75.00
9 µg in 300 µL (1)
USD 47.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 140.00
9 µg in 300 µL (1)
USD 26.00
30 µg in 1 mL (1)
USD 51.00

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