Anti-TCR Vβ5.1 antibodies, human

Anti-TCR Vβ5.1 antibodies, human

Clone: REA1062 | Dilution: 1:50
Clone REA1062 recognizes the human variable beta 5.1 subunit of the α/β T cell receptor (TCR Vβ5.1), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.1 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. REA1062 does not recognize Vβ5.2 or Vβ5.3.
Additional information: Clone REA1062 displays negligible binding to Fc receptors.

Alternative names

TCR Vb5.1, TCR Vbeta5.1, V beta 5.1

Technical specifications

  • Antigen: TCR Vβ5.1
  • Clone: REA1062
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vb5.1, TCR Vbeta5.1, V beta 5.1
  • Entrez Gene ID: 28614
  • Molecular mass of antigen [kDa]: 10
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, Biotin
  • Selected references

    1. Concannon, P. et al. (1986) Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc. Natl. Acad. Sci. U.S.A. 83(17): 6598-6602
    2. Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40(1): 27-36
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