Anti-PSA-NCAM antibodies, human, mouse, rat

Anti-PSA-NCAM antibodies, human, mouse, rat

Clone: 2-2B
The Anti-PSA-NCAM antibody recognizes an epitope on human, mouse, and rat polysialic acid (PSA) which, in vertebrates, is found linked to the extracellular domain of the neural cell adhesion molecule (NCAM, CD56). PSA-NCAM, the highly polysialated form of NCAM, is predominantly expressed in embryonic and neonatal neural tissue. In adult mammalian brain PSA-NCAM expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ) and the dentate gyrus of the hippocampus. PSA-NCAM is a marker for immature neuronal-committed progenitors that are permanently generated in the SVZ and migrate along a well-defined pathway, the rostral migratory stream, into the olfactory bulb where they differentiate into GABAergic and dopaminergic interneurons. Antibodies against PSA-NCAM have also been used to immunomagnetically isolate neuronal progenitors from postnatal mice and rat forebrain.

Alternative names


Technical specifications

  • Antigen: PSA-NCAM
  • Clone: 2-2B
  • Isotype: mouse IgM
  • Isotype control: Mouse IgM – isotype control antibodies
  • Alternative names of antigen: NCAM1, CD56, MSK39, NCAM, E-NCAM, NCAM-1, NCAM-C
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 1 mL
USD 445.00

Related products

5 products available | view all