Anti-Ly-6C antibodies, mouse

Anti-Ly-6C antibodies, mouse

Clone: 1G7.G10 | Dilution: 1:50
Ly-6C is a 14-17 kDa GPI-linked cell surface antigen that belongs to the Ly-6 family of murine surface glycoproteins. It is expressed on monocytes in the bone marrow and shortly after their migration into the circulation. Moreover, Ly-6C is expressed on memory T cells and CD11
low
CD45R(B220)
+
mPDCA1
+
plasmacytoid dendritic cells (pDCs) in different organs.

Alternative names

Ly-6C1, Ly-6C.2, Ly-6C2

Technical specifications

  • Antigen: Ly-6C
  • Clone: 1G7.G10
  • Isotype: rat IgG2a
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: Ly-6C1, Ly-6C.2, Ly-6C2
  • Entrez Gene ID: 100041546
  • Molecular mass of antigen [kDa]: 9
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin, APC-Vio770, PE
  • Selected references

    1. Curtsinger, J. M. et al. (1998)
      CD8
      +
      memory T cells (CD44
      high
      , Ly-6C
      +
      ) are more sensitive than naive cells to (CD44
      low
      , Ly-6C
      -
      ) to TCR/CD8 signaling in response to antigen.
      J. Immunol. 160: 3236-3243
    2. Schlueter, A. J. et al. (1997) Distribution of Ly-6C on lymphocyte subsets: I. Influence of allotype on T lymphocyte expression. J. Immunol. 158: 4211-4222
    3. Sunderkötter, C. et al. (2004) Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J. Immunol. 172: 4410-4417
    4. Hänninen, A. et al. (1997)
      Ly-6C regulates endothelial adhesion and homing of CD8
      +
      T cells by activating integrin-dependent adhesion pathways.
      Proc. Natl. Acad. Sci. U.S.A. 94: 6898-6903
    5. Shevach, E. M. and Korty, P. E. (1989) Ly-6: a multigene family in search of a function. Immunol. Today 10: 195-220
Product options: 3
30 µg in 200 µL (1)
USD 55.00
30 µg in 200 µL (1)
USD 55.00
30 µg in 200 µL (1)
USD 140.00

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