Anti-Ly-6B.2 antibodies, mouse

Anti-Ly-6B.2 antibodies, mouse

Clone: REA115 | Dilution: 1:10
Clone REA115 recognizes Ly-6B.2, a member of the lymphocyte antigen 6 (Ly-6) superfamily and is located on chromosome 15 as the other members of the murine Ly-6 family. The Ly-6 family members are normally GPI-anchored, cysteine-rich cell surface molecules. Expression of Ly-6B.2 antigen has been reported on neutrophils, bone marrow restricted progenitors, monocytes, and is lost during the differentiation of monoytes into tissue resident macrophages or dendritic cell phenotype. High expression of Ly-6B.2 is also associated with inflammatory cell repertoire including monocytes and certain populations of activated macrophages present during infections.
Additional information: Clone REA115 displays negligible binding to Fc receptors.

Alternative names

LY6B

Technical specifications

  • Antigen: Ly-6B.2
  • Clone: REA115
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: LY6B
  • Entrez Gene ID: 110453
  • Distribution of antigen: neutrophils, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Rosas, M. et al. (2010) The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J. Leukoc. Biol. 88: 169-180
    2. Hirsch, S. et al. (1983) Polymorphic expression of a neutrophil differentiation antigen revealed by monoclonal antibody 7/4. Immunogenetics 18(3): 229-239
Product options: 13
9 µg in 300 µL (1)
USD 20.00
30 µg in 1 mL (1)
USD 45.00
9 µg in 300 µL (1)
USD 41.00
30 µg in 1 mL (1)
USD 56.00
9 µg in 300 µL (1)
USD 50.00
30 µg in 1 mL (1)
USD 80.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 52.00
30 µg in 1 mL (1)
USD 140.00
30 µg in 1 mL (1)
USD 136.00
9 µg in 300 µL (1)
USD 25.00
30 µg in 1 mL (1)
USD 55.00

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