Anti-Ly-49G antibodies, mouse

Anti-Ly-49G antibodies, mouse

Clone: REA1022 | Dilution: 1:50
Clone REA1022 recognizes the type II transmembrane protein Ly-49G, which is a MHC class I receptor also known as Kira-7. It is expressed on NK, NKT, and T cells. It is reported that the binding of Ly-49G with its ligand leads to inhibition of NK cells, T cells cytotoxicity, cytokine production, and proliferation. The antibody reacts with Ly49G receptor of A/J, BALB/c, C3H, CBA,129, FVB, and SJL mice, but not C57BL/6 mice.
Additional information: Clone REA1022 displays negligible binding to Fc receptors.

Alternative names

Klra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2

Technical specifications

  • Antigen: Ly-49G
  • Clone: REA1022
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Klra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2
  • Entrez Gene ID: 16638
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, Biotin
  • Selected references

    1. Makrigiannis, A. P. et al. (2004) Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing. J. Immunol. 172: 1414-1425
    2. Rouhi, A. et al. (2007) Plasticity of Ly49g expression is due to epigenetics. Mol. Immunol. 44(5): 821-826
Product options: 3
30 µg in 200 µL (1)
USD 45.00
30 µg in 200 µL (1)
USD 55.00
30 µg in 200 µL (1)
USD 55.00

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