Anti-IgE antibodies, human

Anti-IgE antibodies, human

Clone: MB10-5C4 | Dilution: 1:50
Anti-IgE antibodies react with the IgE isotype of human immunoglobulins. IgE is the shortest-lived immunoglobulin with a half-life of two days in serum. IgE plays an important role in allergy. It is especially associated with type 1 hypersensitivity, where IgE shows high-affinity binding to Fc receptors expressed on the surface of mast cells. Antigen binding to Fc receptor–bound IgE upon re-exposure to specific allergens results in degranulation and the release of a variety of mediators, such as histamine and cytokines.
IgE has two main receptors: the high-affinity receptor FcεRI, which is expressed only on mast cells and basophils, and the low-affinity receptor FcεRII (CD23), which is expressed on B cells.

Alternative names

IGHE

Technical specifications

  • Antigen: IgE
  • Clone: MB10-5C4
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: IGHE
  • Entrez Gene ID: 3497
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, Biotin, pure
Product options: 11
for 30
tests
(1)
USD 83.00
for 100
tests
(1)
USD 241.00
for 30
tests
(1)
USD 104.00
for 100
tests
(1)
USD 278.00
for 30
tests
(1)
USD 122.00
for 100
tests
(1)
USD 288.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 315.00
for 30
tests
(1)
USD 82.00
for 100
tests
(1)
USD 242.00
100 µg in 1 mL
USD 140.00

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