Anti-GM-CSF antibodies, human

Anti-GM-CSF antibodies, human

Clone: REA1215 | Dilution: 1:50
Clone REA1215 recognizes the human granulocyte macrophage colony-stimulating factor (GM-CSF), which is a hematopoietic growth factor that is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors. It also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF strongly chemoattracts neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.
Additional information: Clone REA1215 displays negligible binding to Fc receptors.

Alternative names

CSF2

Technical specifications

  • Antigen: GM-CSF
  • Clone: REA1215
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: CSF2
  • Entrez Gene ID: 1437
  • Molecular mass of antigen [kDa]: 14
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: macrophages, T cells, fibroblasts, endothelial cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770
Product options: 8
for 30
tests
(1)
USD 106.00
for 100
tests
(1)
USD 284.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 294.00
for 30
tests
(1)
USD 148.00
for 100
tests
(1)
USD 325.00
for 30
tests
(1)
USD 138.00
for 100
tests
(1)
USD 330.00